Tuesday, Dec 13th
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| 8:30-8:45 am |
Jonathan Crowston, Franz Grus & Keith Martin |
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Welcome and Introduction |
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| 08:45 - 10:00 am |
Session I: Neural replacement and regeneration |
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[Moderators: Martin, Fischer] |
| 8:45 - 9:10 |
Alice Pebay |
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Human pluripotent stem cells for retinal disease |
| 09:10 - 9:35 |
Elena Vecino |
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Microtubule polymerisation during RGC axon regeneration |
| 9:35 - 10:00 |
Ann Logan |
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siRNA and regeneration |
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30 min tea break
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| 10:30 - 11:55 am |
Session II: Modulating neuronal function |
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[Moderators: Mackey, Bell] |
| 10:30 - 10:55 |
Jessica Kwok |
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Perineural net mediated neuroplasticity |
| 10:55 - 11:20 |
Steven Petrou |
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Taming the excitable cell |
| 11:20-11:45 |
Yves Barde |
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Neurotrophins in development and disease |
| 11:45 - 11:55 |
George Kong |
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Improvement of Visual Field following successful Trabeculectomy is related to Preoperative Mean Deviation |
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lunch and afternoon break
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| 05:30 - 6:40 pm |
Session III: Gene Therapy |
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[Moderators: Crowston, Pebay] |
| 5:30 - 5:55 |
David Mackey |
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Gene based therapies for LHON hype or hope |
| 5:55 - 6:20 |
Andrew Osborne |
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Targetting RGC with gene therapy |
| 6:20 - 6:30 |
Kim Lemmens |
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Dendritic remodeling as fuel for axonal regeneration in the injured zebrafish retinotectal system? Primary insights from MMP inhibitory research |
| 6:30 -6:40 |
Lien Andries |
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MMP-2 as a modulator of dendritic and axonal responses in the injured mammalian central nervous system |
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Wednesday, Dec 14th
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| 08:30 - 10:05 am |
Session IV: Neuroinflammation and glia |
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[Moderators: Karadottir, Williams] |
| 8:30 - 8:55 |
Kristian Franze |
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Microglial mechanics |
| 8:55 - 9:20 |
Crawford Downs |
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Astrocyte and biomechanics |
| 9:20 - 9:45 |
James Tribble |
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Reconstruction of RGCs in human glaucomatous tissue using serial block face electron microscopy |
| 9:45 - 9:55 |
Vanessa Beutgen |
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Profiling of autoantibodies in sera of patients with POAG by serological proteome analysis (SERPA) |
| 9:55 - 10:05 |
Carsten Schmelter |
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Peptides of the variable region of antibodies as potential biomarker candidates in primary open-angle glaucoma (POAG). |
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20 min tea break
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| 10:25 - 12:05 |
Session V: Mitochondria, stress and power |
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[Moderators: Levkovitch, Morgan] |
| 10:25 - 10:50 |
Christian Behl |
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Autophagy - a source of power |
| 10:50 - 11:15 |
Pete Williams |
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NAD supply critically modulates mitochondrial vulnerability and neurodegeneration in aged mice |
| 11:15 - 11:40 |
Robert Casson |
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Oxidative Stress at the Optic Nerve Head in Experimental Glaucoma |
| 11:40 - 11:55 |
Julia Teister |
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Fluorescence lifetime imaging of the ocular fundus in healthy and diseased rats |
| 11:55 - 12:05 |
Fabian Anders |
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Intravitreal injection of β-crystallin B2 improves retinal ganglion cell survival in an experimental animal model of glaucoma |
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lunch and afternoon break
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| 05:30 - 7:05 pm |
Session VI: Regeneration and immunosenescence |
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[Moderators: Vecino, Logan] |
| 5:30 - 5:55 |
Dietmar Fischer |
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Role of GSK3 activity in optic nerve regeneration |
| 5:55 - 6:20 |
Rossella Russo |
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Changing the fate of retinal ganglion cells following retinal ischemia: is autophagy the way? |
| 6:20 - 6:45 |
Richard Eva |
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"Axonal transport as a target for enhancing |
| CNS regeneration" |
| 6:45 - 7:05 |
Anton Hommer |
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Hurdles on the way from science to the patient |
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Thursday, Dec 15th
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| 08:30 - 10:25 am |
Session VII: Neurotrophins, neuroprotection, repair |
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[Moderators: Downs , Inatani] |
| 8:30 - 8:55 |
James Morgan |
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Protecting dendrites |
| 8:55 - 9:20 |
Flora Hui |
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Optimising ERG for monitoring inner retinal function-moving from the lab into the clinic |
| 9:20 - 9:45 |
Thora Karadottir |
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Regulation of remyelination |
| 9:45 - 10:10 |
Bjoern Neumann |
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remyelination of regenerating axons |
| 10:10 - 10:25 |
Katharina Bell |
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Neurotrophins involved in neuroprotective antibody effect |
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25 min tea break
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| 10:50 - 12:05 am |
Session VIII: Advances in imaging |
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[Moderators: Grus, Morgan] |
| 10:50 - 11:15 |
Xavier Hadoux |
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the promise of hyperspectral imaging |
| 11:15 - 11:40 |
Andy McNaught |
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Imaging oxygen levels in the retina |
| 11:40 - 12:05 |
Masaru Inatani |
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Mitochondrial trafficking |
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lunch and afternoon break
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| 05:30 - 6:15 pm |
Session IX: Translation and commercialization |
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[Moderators: Petrou, Osborne] |
| 5:30 - 5:55 |
Stefano Gandolfi |
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Current unmet clinical challenges |
| 5:55 - 6:05 |
Kota Sato |
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The neuroprotective effect of latanoprost after optic nerve transection acts via OATP2B1-mediated klotho fragmentation |
| 6:05 - 6:15 |
Elena Ioyleva |
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Opportunities OCT to study the asymmetry of optic disc changes depending on the duration of multiple sclerosis. |
